Synthesis of a 6H-Pyrazolo[4,5,1-de]acridin-6-one Derivative: A Useful Intermediate of Antitumour Agents

Autor: Yukiteru Mimura, Shinji Tomioka, Toru Sugaya, Takashi Mimura, Masanori Ikuta, Nobuyuki Kato, Masaji Fujisawa-shi Kasai
Rok vydání: 1994
Předmět:
Zdroj: Synthesis. 1994:73-76
ISSN: 1437-210X
0039-7881
Popis: A 6H-pyrazolo[4,5,1-de]acridin-6-one derivative, a useful intermediate of antitumor agents, was prepared by a facile synthetic route from 2-bromobenzoic acid and 6-nitroindazole involving a halogenocopper(I)-catalyzed Ullmann coupling reaction and Friedel-Crafts cyclization.
Databáze: OpenAIRE