Genetic/genomic analysis of signal transduction pathways using cDNA microarray technology

Autor: Aldo Massimi, Joerg Heyer, Erwin P. Bottinger, Anita B. Roberts, Ester Piek, Rongguang Yang, Yaw-Ching Yang, Raju Kucherlapati
Rok vydání: 1999
Předmět:
Zdroj: Nature Genetics. 23:34-34
ISSN: 1546-1718
1061-4036
DOI: 10.1038/14270
Popis: cDNA microarray technology provides a novel approach to identify individual target genes and survey global genetic programs under the control of specific signalling pathways in mammalian systems. Smad2 and Smad3 are highly homologous members of the receptor-regulated subfamily of Smad proteins with a central role in TGF- signalling and target gene regulation.
Databáze: OpenAIRE