ChemInform Abstract: Synthesis of Some Halogenated and Disubstituted Amino Benzylacyclouridine Derivatives

Autor: Shih-Hsi Chu, Elizabeth C. Rowe, Zhi-Hao Chen, Bai-Chuan Pan
Rok vydání: 2010
Předmět:
Zdroj: ChemInform. 23
ISSN: 0931-7597
DOI: 10.1002/chin.199248280
Popis: 1'-Halogenomethyl, 1'-azidomethyl and 1'-disubstituted aminomethyl derivatives of BAU (5-benzylacyclouridine) and BBAU (5-benzyloxybenzylacyclouridine) were synthesized in the course of our studies of benzylacyclouridines. Two new and more convenient preparations of the previously known aminomethyl-and hydroxyymethyl-parent compounds of these two series, AM-BAU, AM-BBAU and HM-BBAU are also reported. These compounds were synthesized during a search for potential antiviral agents and pyrimidine phosphorylase inhibitors
Databáze: OpenAIRE