Additive inheritance of histone modifications in Arabidopsis thaliana intra-specific hybrids
| Autor: | Marie-Laure M. Magniette, Ali Mohammad Banaei Moghaddam, Michael Seifert, Raheleh Karimi Ashtiyani, Andreas Houben, François Roudier, Vincent Colot, Caroline Berard, Michael Florian Mette |
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| Rok vydání: | 2011 |
| Předmět: |
0106 biological sciences
Genetics 0303 health sciences Tiling array biology Cell Biology Plant Science Epigenome ChIP-on-chip 01 natural sciences Chromatin 03 medical and health sciences Histone Histone methylation biology.protein Chromatin immunoprecipitation 030304 developmental biology 010606 plant biology & botany Epigenomics |
| Zdroj: | The Plant Journal. 67:691-700 |
| ISSN: | 0960-7412 |
| DOI: | 10.1111/j.1365-313x.2011.04628.x |
| Popis: | Plant genomes are earmarked with defined patterns of chromatin marks. Little is known about the stability of these epigenomes when related, but distinct genomes are brought together by intra-species hybridization. Arabidopsis thaliana accessions and their reciprocal hybrids were used as a model system to investigate the dynamics of histone modification patterns. The genome-wide distribution of histone modifications H3K4me2 and H3K27me3 in the inbred parental accessions Col-0, C24 and Cvi and their hybrid offspring was compared by chromatin immunoprecipitation in combination with genome tiling array hybridization. The analysis revealed that, in addition to DNA sequence polymorphisms, chromatin modification variations exist among accessions of A. thaliana. The range of these variations was higher for H3K27me3 (typically a repressive mark) than for H3K4me2 (typically an active mark). H3K4me2 and H3K27me3 were rather stable in response to intra-species hybridization, with mainly additive inheritance in hybrid offspring. In conclusion, intra-species hybridization does not result in gross changes to chromatin modifications. |
| Databáze: | OpenAIRE |
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