| Autor: |
Cut Meurah Yeni, Zinatul Hayati, Sarjani M. Ali, Hasanuddin Hasanuddin, Rusnaidi Rusnaidi, Cut Rika Maharani |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Open Access Macedonian Journal of Medical Sciences. 11:293-298 |
| ISSN: |
1857-9655 |
| DOI: |
10.3889/oamjms.2023.11196 |
| Popis: |
Background: Pregnant women are vulnerable against COVID-19 infection due to physiological and immunological changes. COVID-19 in pregnancy affects fetal well-being with a potential for vertical infection. Materials and Method: This study aims to determine the incidence of vertical infection and anti-SARS-CoV-2 antibodies in infants born to mothers with positive COVID-19 infection. Amniotic fluid, swabs of the newborn's nasopharynx and oropharynx, and swabs of the placenta were examined using RT-PCR for SARS-CoV-2. Serological examination was performed by Electro-Chemiluminescence Immunoassay (ECLIA) on infant’s blood. Result: Four of 33 pregnant women gave birth to infants positive SARS-CoV-2 infection. RT-PCR examination of all amniotic fluid and placental swabs were negative for SARS-CoV-2. Four of 33 infants (12.1%) showed negative PCR results but positive SARS-CoV-2 antibodies, another 4 newborns (12.1%) showed positive PCR results, but no SARS-CoV-2 antibodies detected. The remaining 25 babies (75.8%) showed both negative PCR and serologic results. Conclusion: No evidence of vertical transmission found in this study. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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