Facile synthesis of enantiopure 1,1′-binaphthyl-2,2′-dicarboxylic acid via lipase-catalyzed kinetic resolution
Autor: | Toshiyuki Furutani, Masahiko Seki, Masanori Hatsuda, Ritsuo Imashiro |
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Rok vydání: | 1999 |
Předmět: | |
Zdroj: | Tetrahedron: Asymmetry. 10:4763-4768 |
ISSN: | 0957-4166 |
DOI: | 10.1016/s0957-4166(99)00555-8 |
Popis: | Enantiopure 1,1′-binaphthyl-2,2′-dicarboxylic acids ( R )- 1 and ( S )- 1 have been synthesized through the lipase-catalyzed kinetic resolution of the racemic 2,2-bis(hydroxymethyl)-1,1′-binaphthyl (±)- 2 and subsequent oxidation of the hydroxymethyl groups. |
Databáze: | OpenAIRE |
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