Echo time dependence of observedT1in the human lung

Autor:	Felix A. Breuer, Jürgen Biederer, Mark O. Wielpütz, Peter M. Jakob, Simon M. F. Triphan, Hans-Ulrich Kauczor, Bertram J. Jobst
Rok vydání:	2015
Předmět:	Physics Diagnostic information Pathology medicine.medical_specialty Echo time Echo (computing) Inversion recovery Human lung Nuclear magnetic resonance medicine.anatomical_structure Healthy volunteers Lung imaging medicine Radiology Nuclear Medicine and imaging Lung tissue
Zdroj:	Journal of Magnetic Resonance Imaging. 42:610-616
ISSN:	1053-1807
Popis:	Background This work is intended to demonstrate that T1 measured in the lungs depends on the echo time (TE) used. Measuring lung T1 can be used to gain quantitative morphological and functional information. It is also shown that this dependence is particularly visible when using an ultra-short TE (UTE) sequence with TE well below 1 ms for T1 quantification in lung tissue, rather than techniques with TE on the order of 1–2 ms. Methods The lungs of 12 healthy volunteers (aged 22 to 33 years) were examined at 1.5 Tesla. A segmented inversion recovery Look-Locker multi-echo sequence based on two-dimensional UTE was used for independent T1 quantification at five TEs between TE1 = 70 μs and TE5 = 2.3 ms. Results The measured T1 was found to increase gradually with TE from 1060 ± 40 ms at TE1 to 1389 ± 53 ms at TE5 (P
Databáze:	OpenAIRE
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