Atypical Spindle Cell Lesion of Larynx: A Rare Benign Condition mimicking Malignancy

Autor:	Sridhar R Dandala, Achyuth Panuganti, Pindicura Kumuda
Rok vydání:	2017
Předmět:	Larynx Benign condition Pathology medicine.medical_specialty business.industry 030206 dentistry Malignancy medicine.disease 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure 030220 oncology & carcinogenesis Medicine business Spindle cell lesion
Zdroj:	International Journal of Phonosurgery & Laryngology. 7:31-35
ISSN:	2231-3702 2230-7508
DOI:	10.5005/jp-journals-10023-1139
Popis:	Atypical spindle cell lesion of larynx is a very rare condition usually misdiagnosed as malignant spindle cell tumor, requiring immunohistochemical (IHC) studies for reaching a correct diagnosis. We present a case of a 75-year-old male patient, who presented to the ear, nose, and throat casualty in stridor, and was tracheostomized. Videolaryngoscopy revealed a huge irregular growth filling the supraglottis. Biopsy of the growth suggested a reactive fibroblastic proliferation with atypia. The patient was again subjected to biopsy and it revealed well-differentiated squamous cell carcinoma (SCC). Total laryngectomy was done. The specimen on histopathological examination revealed atypical spindle cell lesion, and on IHC revealed a benign inflammatory spindle cell neoplasm. Here, we discuss the difficulty in making a decision on definitive treatment for such a condition and the importance of histopathological diagnosis of this condition for better understanding of its management. How to cite this article Dandala SR, Panuganti A, Kumuda P. Atypical Spindle Cell Lesion of Larynx: A Rare Benign Condition mimicking Malignancy. Int J Phonosurg Laryngol 2017;7(1):31-35.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ad8bc4fd8bc72d8b673e9430145f762b https://doi.org/10.5005/jp-journals-10023-1139 Zobrazit plný text záznamu