Thermosensitive copolymer synthesized by controlled living radical polymerization: Phase behavior of diblock copolymers of poly(N-isopropyl acrylamide) families
| Autor: | Yo-Ying Chuang, Whe-Yi Chiang, Syang-Peng Rwei, Tun-Fun Way |
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| Rok vydání: | 2015 |
| Předmět: |
Materials science
Polymers and Plastics Radical polymerization 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences Surfaces Coatings and Films End-group Living free-radical polymerization Chain-growth polymerization Polymerization Polymer chemistry Materials Chemistry Living polymerization Reversible addition−fragmentation chain-transfer polymerization 0210 nano-technology Ionic polymerization |
| Zdroj: | Journal of Applied Polymer Science. 133 |
| ISSN: | 0021-8995 |
| DOI: | 10.1002/app.43224 |
| Popis: | In this study, we prepared a series of thermosensitive polymers with low polydispersity index (PDI) values by nitroxide-mediated controlled radical polymerization (NMRP) with 2,2,6,6-tetramethyl-1-piperdinyloxy nitroxide (TEMPO) as a stable nitroxide-free radical. Poly(N-isopropyl acrylamide) (PNIPAAm)-block-poly(N-tert-butyl acrylamide) (PNTBA) was successfully synthesized, first, through polymerization with N-isopropyl acrylamide to obtain the reactive polymer PNIPAAm-TEMPO and, second, through polymerization by the addition of N-tert-butyl acrylamide (NTBA). The added molar fraction of NTBA during the second polymerization was adjusted accordingly to obtain the final polymerization product, a thermosensitive polymer (PNIPAAm-block-PNTBA), which had a targeted lower critical solution temperature (LCST). The result shows that the synthesis method used in this study effectively controlled the formation of the polymer to obtain a low PDI. The thermosensitive block copolymer, PNIPAAm-b-PNTBA (molar ratio = 9:1), with LCSTs in the range 27.7–39.8°C, was obtained through controlled living radical polymerization with PNIPAAm–TEMPO. Specifically, the 5 wt % aqueous solution of PNIPAAm-b-PNTBA (molar ratio = 9:1) had an LCST of 37.4°C; this was close to body temperature, 37°C. The 5 wt % aqueous solution of PNIPAAm-b-PNTBA (molar ratio = 9:1) showed potential for use in biomedical applications. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016, 133, 43224. |
| Databáze: | OpenAIRE |
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