Correlation between serum ferritin and severity of alopecia areata
| Autor: | T H Bijayanti Devi, Romita Bachaspatimayum, Yogesh Devaraj |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
integumentary system medicine.diagnostic_test biology business.industry Ferritin levels Physical examination Alopecia areata Hair follicle medicine.disease Gastroenterology Iron store Ferritin medicine.anatomical_structure Internal medicine biology.protein Medicine Outpatient clinic skin and connective tissue diseases business Serum ferritin |
| Zdroj: | IP Indian Journal of Clinical and Experimental Dermatology. 5:336-339 |
| ISSN: | 2581-4729 2581-4710 |
| DOI: | 10.18231/j.ijced.2019.070 |
| Popis: | Introduction: Alopecia areata is a common cause of patchy hair loss. It is an autoimmune disorder with unpredictable course. Total body iron store is an integral factor in the development of hair follicle. Numerous studies have been done to find the relationship between serum ferritin and alopecia areata with contradictory findings. Materials and Methods: A cross-sectional study was carried out in Dermatology Outpatient Department in a tertiary care hospital. All new cases of alopecia areata, aged 1 to 60 years were included. A detailed history was taken and clinical examination conducted. Serum Ferritin of all patients was measured. Clinical severity of alopecia areata was assessed and compared with the ferritin levels. Analysis of data was done by SPSS software, version 16.0. Results: A total of 36 patients including 23 males and 13 females were studied. Mild AA was seen in 11 patients including 6 males and 5 females. Moderate AA was seen in 25 patients including 17 males and 8 females. The mean serum ferritin in males with mild AA was 179.4 ng /ml and those with moderate AA was 125 ng /ml. In females, mean serum ferritin in mild AA was 64.27 ng /ml and in moderate AA it was 46.46 ng/ml. Conclusion: Our study showed that with increase in severity of AA, there was a decrease in mean serum ferritin both in males and females. This implies that the severity of AA is influenced by serum ferritin levels. Since our study did not include controls, no postulates can be made in this regard. Further studies with larger number of subjects are essential to know the exact role of ferritin in alopecia areata and its severity. Keywords: Alopecia areata, Serum ferritin, Autoimmunity, Non cicatricial, Severity. |
| Databáze: | OpenAIRE |
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