Bacillus subtilis Spore Surface Display Technology: A Review of Its Development and Applications
| Autor: | Qi Xianghui, Miaomiao Yang, Wen Li, Hossain M. Zabed, Yuan Jiao, Zhang Guoyan, Sun Wenjing, Guo Qi, An Yingfeng |
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| Rok vydání: | 2019 |
| Předmět: |
0106 biological sciences
Cell Surface Display Techniques Environmental pollution General Medicine Protein engineering Bacillus subtilis Biology Gene engineering biology.organism_classification 01 natural sciences Applied Microbiology and Biotechnology Surface display Metabolic engineering 010608 biotechnology High activity Biochemical engineering Biotechnology |
| Zdroj: | Journal of Microbiology and Biotechnology. 29:179-190 |
| ISSN: | 1738-8872 1017-7825 |
| Popis: | Bacillus subtilis spore surface display (BSSD) technology is considered to be one of the most promising approaches for expressing heterologous proteins with high activity and stability. Currently, this technology is used for various purposes, such as the production of enzymes, oral vaccines, drugs and multimeric proteins, and the control of environmental pollution. This paper presents an overview of the latest developments in BSSD technology and its application in protein engineering. Finally, the major limitations of this technology and future directions for its research are discussed. |
| Databáze: | OpenAIRE |
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