Nebivolol nanoparticles: a first catalytic use in Biginelli and Biginelli-like reactions

Autor:	Utpal Jana, Pranjit Barman, Anamika Khaskel, Subir Kumar Maiti
Rok vydání:	2018
Předmět:	010405 organic chemistry Atomic force microscopy Chemistry Organic Chemistry Nanoparticle General Chemistry 010402 general chemistry 01 natural sciences Combinatorial chemistry Catalysis Nebivolol 0104 chemical sciences medicine medicine.drug
Zdroj:	Canadian Journal of Chemistry. 96:1021-1025
ISSN:	1480-3291 0008-4042
DOI:	10.1139/cjc-2017-0621
Popis:	Herein, we report the catalytic activity of nebivolol nanoparticles a novel organocatalyst for the synthesis of DHPMs and DHPM-5-carboxamides. The nanoparticles are confirmed by DSC, TEM, AFM, and IR spectroscopy. The catalyst can be readily recovered and reused for the next four runs without any significant impact on the yields of the products. The products are fully characterized by FTIR, 1H NMR, 13C NMR, and distortionless enhanced polarization transfer (DEPT) NMR. The methodology adopted here offers several advantages such as solvent-free reaction, low loading of catalyst, short reaction times, and quantifiable yields.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ad73a73fa2e4be645d0e25c41d40beb2 https://doi.org/10.1139/cjc-2017-0621 Zobrazit plný text záznamu Plný text ve formátu PDF