Specific immunotherapy in the treatment of Culicoides hypersensitive horses: A double-blind study

Autor:	Ellis C. Greiner, Joy L. Barbet, Diane Bevier
Rok vydání:	1990
Předmět:	Veterinary medicine biology medicine.medical_treatment Horse General Medicine Immunotherapy Culicoides biology.organism_classification Culicoides variipennis Sweet itch Ivermectin Antigen Immunity Immunology medicine medicine.drug
Zdroj:	Equine Veterinary Journal. 22:232-235
ISSN:	2042-3306 0425-1644
Popis:	Summary Fourteen privately owned horses completed a six month, controlled, double-blind trial to assess the efficacy of immunotherapy using an aqueous extract of whole, unfed Culicoides variipennis in the treatment of Culicoides hypersensitivity. Selected horses had a history of a seasonal, pruritic dermatitis, clinical signs and distribution compatible with Culicoides hypersensitivity, failed to improve in response to ivermectin therapy, and reacted to several dilutions of Culicoides extracts without significant reactivity to other possible allergens including insects, moulds and feeds. One horse from the control group (n=8) and one from the test group (n=6) improved. Statistically, there was no significant difference between horses on Culicoides antigen and control horses. In each group, four owners thought that their horses had improved.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ad6cebda42eb92a7bccca6d59ad4dfb3 https://doi.org/10.1111/j.2042-3306.1990.tb04258.x Zobrazit plný text záznamu Plný text