ChemInform Abstract: Synthesis and Characterization of Oligodeoxynucleotides Containing 5′,8-Cyclopurine-2′-deoxyribonucleosides
Autor: | Didier Gasparutto, Jean Cadet, Didier Molko, Anthony Romieu |
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Rok vydání: | 2010 |
Předmět: | |
Zdroj: | ChemInform. 30 |
ISSN: | 1522-2667 0931-7597 |
DOI: | 10.1002/chin.199943249 |
Popis: | Oligodeoxynucleotides containing the two 5′R and 5′S diastereoisomers of 5′,8-cyclo-2′-deoxyadenosine (CyclodAdo) and 5′,8-cyclo-2′-deoxyguanosine (CyclodGuo) have been synthesized using the phosphoramidite chemistry. The structural assignment and a few biochemical features of these modified DNA fragments are reported. |
Databáze: | OpenAIRE |
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