A novel family of small molecule HIF-1 alpha stabilizers for the treatment of diabetic wounds; an integrated in silico, in vitro, and in vivo strategy
| Autor: | Esakkimuthukumar M., Akey Krishna Swaroop, Sunil Kumar Patnaik, Rajesh Kumar R., Praveen T. K., Mudavath Ravi Naik, Jubie S. |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | RSC Advances. 12:31293-31302 |
| ISSN: | 2046-2069 |
| Popis: | 2,3,5-Tri substituted pyrazole analogues are identified as HIF-1α mimetics, which block the VHL interaction for diabetic wound healing therapy. |
| Databáze: | OpenAIRE |
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