Translating Knowledge from Bench to Bedside: The Controversial Social Life of t-PA

Autor: Charles Mather, Liam Taylor, Usher Fleising
Rok vydání: 2004
Předmět:
Zdroj: Risk Management. 6:49-60
ISSN: 1743-4637
1460-3799
DOI: 10.1057/palgrave.rm.8240179
Popis: Knowledge translation involves organizational and practical transformation. This paper examines it in a medical setting, using a case study of the development of a medicine (t-PA) ‘from bench to bedside’. The case study reveals the contentious character of knowledge claims and knowledge translation, the role of ideology and the symbology of power in knowledge translation, and that knowledge translation can work at an organizational level yet remain suspect at the level of practice. We conclude that the case study provides a complement to functional analyses of knowledge translation, illustrating both its political and its organizational context, and the local social-psychological context of therapeutic reform and innovative diffusion.
Databáze: OpenAIRE