Do intraocular Angiotensin II levels, plasma prothrombotic factors and endothelial dysfunction contribute to proliferative diabetic retinopathy?
| Autor: | P. L. Lip, A. F. Jones, D. G. Beevers, M. Headon, G. Y. H. Lip, N. Price |
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| Rok vydání: | 1998 |
| Předmět: |
medicine.medical_specialty
Endothelium business.industry Diabetic retinopathy medicine.disease Fibrinogen Angiotensin II Ophthalmology medicine.anatomical_structure Endocrinology Blood pressure Internal medicine Renin–angiotensin system medicine Hemorheology Endothelial dysfunction business hormones hormone substitutes and hormone antagonists medicine.drug |
| Zdroj: | Acta Ophthalmologica Scandinavica. 76:533-536 |
| ISSN: | 1395-3907 |
| Popis: | PURPOSE To investigate whether diabetic retinopathy (DR) is associated with abnormalities in: (i) aqueous humour Angiotensin I (Ang I) and Angiotensin II (Ang II) levels; and (ii) plasma Ang I, soluble P-selectin, lipoprotein (a) (Lp(a)), endothelial markers and haemorheological abnormalities. METHODS Cross-sectional study of diabetic patients and healthy controls undergoing cataract surgery. RESULTS 21 diabetic patients (12 males; mean age 67.0 years) were studied. Plasma levels of Ang II were lower in diabetics compared with controls (p |
| Databáze: | OpenAIRE |
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