A biointegration of microand nanocrystalline hydroxyapatite: problems and perspectives

Autor: A. S. Senotov, I. S. Fadeeva, A. S. Pankratov, Yu B. Yurasova, Vladimir S. Akatov, P. O. Kirsanova, V. V. Minaychev
Rok vydání: 2018
Předmět:
Zdroj: Genes & Cells. 13:46-51
ISSN: 2500-2562
2313-1829
DOI: 10.23868/201811032
Popis: Сalcium phosphate materials have been applied in clinical medicine since 1920. Among calcium phosphate materials, hydroxyapatite (HAp) is traditionally of the greatest interest, because HAp is the main inorganic component of bone tissues. However, synthetic HAр ceramics subjected to high-temperature processing, as it turned out, have a rather limited use as an osteoplastic material. Since 1990, due to advances in chemical technology, new materials of pasty nanocrystalline HAр have been developed, which are promising for the directed influence on the process of bone tissue regeneration. This review briefly summarizes the experimental and clinical data related to the application of micro- and nano-sized hydroxyapatite, and evaluated the potential of pasty nanocrystalline HAp as a material for guided bone regeneration.
Databáze: OpenAIRE