Modifying Influence of Fasting on DNA Synthesis, Cholesterol Metabolism and HMP Shunt Enzymes in Liver Hyperplasia Induced by Lead Nitrate

Autor:	Sandra Dessì, P. Pani, Marina Armeni, Maria Franca Mulas, Batetta B, Donatella Pulisci, Annalisa Carrucciu
Rok vydání:	1988
Předmět:	chemistry.chemical_classification medicine.medical_specialty Mitotic index DNA synthesis Stimulation Mevalonic acid Pentose phosphate pathway Biology chemistry.chemical_compound Endocrinology Enzyme chemistry Internal medicine medicine Shunt (electrical) Pyruvate kinase
Zdroj:	Chemical Carcinogenesis ISBN: 9781475796421
DOI:	10.1007/978-1-4757-9640-7_57
Popis:	Previous studies by Columbano et al.1 have shown that lead nitrate when injected intravenously as a single dose to rats, induces an hyperplastic response in the liver as indicated by an increased DNA synthesis and by an enhanced mitotic index. Liver hyperplasia was accompanied by a stimulation of cholesterol synthesis and hexose-monophosphate (HMP) shunt enzymes2.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ad0af1aba7830f886766e8354b9e7330 https://doi.org/10.1007/978-1-4757-9640-7_57 Zobrazit plný text záznamu