Bicyclic diazasugars 2. Synthesis and structures of L-arabinose and D-ribose analogues

Autor:	N. Kent Dalley, David A. Berges, Liwu Hong
Rok vydání:	1998
Předmět:	Arabinose chemistry.chemical_compound chemistry Bicyclic molecule L-Arabinose Component (thermodynamics) Stereochemistry Organic Chemistry Drug Discovery Ribose Nuclear magnetic resonance spectroscopy Biochemistry
Zdroj:	Tetrahedron. 54:5097-5104
ISSN:	0040-4020
Popis:	Bicyclic diazasugar analogues of L-arabinose and D-ribose have been prepared and characterized by x-ray crystallography and NMR spectroscopy. The crystalline arabinose analogue is the β-anomer in the ring-flipped 1C4 conformation (7), but in D2O solution this is a minor component with the major being the α-anomer in the 4C1 conformation (6). The crystalline ribose analogue is the β-anomer in the 4C1 conformation (10) which is also the major component in D2O solution and is accompanied by a minor form which is probably the α-anomer in the ring-flipped 1C4 conformation (11).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ad03b6bb2dc8e623ede27b1f45151317 https://doi.org/10.1016/s0040-4020(98)00249-x Zobrazit plný text záznamu Full Text from ScienceDirect