| Popis: |
Leaves of Petunia inflata gave the following new steroids: (22 R , 24 S )-1α-acetoxy-24, 25-epoxy-7α-hydroxy-22-nicotinoyloxyergost-4-en-3-one (petuniasterone B 22-nicotinate), (22 R , 24 S )-1α-acetoxy-7α,22-dinicotinoyloxy-24, 25-epoxyergost-4-en-3-one (petuniasterone B 7, 22-dinicotinate), (22 R , 24 S )-7α,22-diacetoxy-24, 25-epoxyergosta- 1, 4-dien-3-one (petuniasterone C 7,22-diacetate), (22 R , 24 S )-24, 25-epoxy-7α-hydroxy-22-nicotinoyloxyergosta-1, 4-dien-3-one (petuniasterone C 22-nicotinate), (22 R , 24 S )-7α-acetoxy-24,25-epoxy-22-nicotinoyloxyergosta-1, 4-dien-3-one (petuniasterone C 7-acetate-22-nicotinate), (22 R , 24 S )-7α, 22-dinicotinoyloxy-24, 25-epoxyergosta-1,4-dien-3-one (petuniasterone C 7, 22-dinicotinate), (22 R , 24 R )-1α-acetoxy-7α,22,24,25-tetrahydroxyergost-4-en-3-one 22,24,25-orthoacetate (petuniasterone S), (22 R , 24 R )-1α-acetoxy-7α,22,24,25-tetrahydroxyergost-4-en-3-one 22,24,25-orthonicotinate (petunianine C). Those compounds having 1α-acetoxy groups are easily converted into the A-ring dienones by mild base. Orthoester and other side chain derivatives may be formed from the 24, 25-epoxides upon acid treatment. |
