Autor: |
H. W. Stewart, N. Q. Quinones, K. L. Howard, E. A. Conroy, J. J. Denton |
Rok vydání: |
1954 |
Předmět: |
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Zdroj: |
Journal of the American Pharmaceutical Association (Scientific ed.). 43:625-628 |
ISSN: |
0095-9553 |
DOI: |
10.1002/jps.3030431016 |
Popis: |
The preparation and anticonvulsant activity of twenty-four new l-heterocyclic-4-substituted carbamyl- and -thiocarbamylpiperazines are presented. Three were prepared by the reaction of 1-diethylcarbamylpiperazine with the appropriate halogen-substituted heterocycle, while the remaining twenty-one were prepared by the reaction of 1-heterocyclic piperazioes with the appropriate isocyanate, isothiocyanate, or substituted carbamyl chloride. Five of these compounds received maximum anticonvulsant rating by the general testing methods employed. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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