Abietane diterpenes with antibiotic activity from the flowers of Salviacanariensis. Reaction of galdosol with diazomethane

Autor:	Lucía S. Andrés, Antonio G. González, Javier G. Luis, Angel G. Ravelo, Juan R. Herrera
Rok vydání:	1989
Předmět:	chemistry.chemical_compound chemistry Stereochemistry medicine.drug_class Diazomethane Organic Chemistry Antibiotics medicine Organic chemistry General Chemistry Rosmaquinone Catalysis Abietane
Zdroj:	Canadian Journal of Chemistry. 67:208-212
ISSN:	1480-3291 0008-4042
DOI:	10.1139/v89-035
Popis:	The new diterpenes canariquinone (9), rosmaquinone (10), and 11-acetoxycarnosic acid (6), together with the already known 7-ethoxyrosmanol (1), 7-methoxyrosmanol (2), and rosmanol (3), were isolated from the flowers of Salviacanariensis. The structure of the new substances was established by a combination of chemical and spectroscopic means. Reaction of galdosol (4), isolated from the aerial part of the same plant, with diazomethane, unexpectedly gave the new homoditerpenes 15 and 16, the structures of which were determined by spectroscopic methods. A mechanism accounting for the formation of these substances is suggested. Keywords: abietane diterpenes, Salvia, Labiatae, antibiotic activity, galdosol reactivity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::acfbc9edcb664b157e5dc7ea1907397a https://doi.org/10.1139/v89-035 Zobrazit plný text záznamu