ChemInform Abstract: Tandem Synthesis of Substituted 2,7-Naphthyridin-1(7H)-ones via Reissert Reaction/Intramolecular Nucleophilic Addition/Oxidation Dehydrogenation

Autor:	Runtao Li, Yu Zhang, Hailiang Tan, Qi Sun, Jie Wang, Yongning Xing
Rok vydání:	2014
Předmět:	Reissert reaction chemistry.chemical_compound Nucleophilic addition Nicotinamide chemistry Tandem Intramolecular force Organic chemistry Dehydrogenation General Medicine Combinatorial chemistry
Zdroj:	ChemInform. 45
ISSN:	0931-7597
DOI:	10.1002/chin.201403178
Popis:	A convenient method for the synthesis of substituted 2,7-naphthyridin-1(7 H )-ones has been developed. This method was carried out starting from a simple nicotinamide salts via a tandem process including Reissert reaction, intramolecular nucleophilic addition and oxidation dehydrogenation. Using this method, a variety of substituted 2,7-naphthyridin-1(7 H )-ones were obtained in good yields.
Databáze:	OpenAIRE
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