Biorecognition on the Surface of Patterned Silicon/Silica and Gold/Silica Slide

Autor: Li Bo Nie, Hao Chang, Quan Guo He, Zhu Chen
Rok vydání: 2012
Předmět:
Zdroj: Applied Mechanics and Materials. :2991-2995
ISSN: 1662-7482
DOI: 10.4028/www.scientific.net/amm.220-223.2991
Popis: As the substrates of biosensor or biomicroarray, silicon, silica and gold matrixes are usually used as the surfaces of bio-recognition. In this research, designed micro-patterned silicon/silica slide and gold/silica slide were utilized respectively as the substrates of DNA and protein detection. The results suggested the detection limit of protein and DNA on silicon/silica slide were 10 μg/L and 10 pM respectively, and those on gold/silica slide were 10 μg/L and 100 pM respectively. The patterned silicon/silica and gold/silica slide could be used as the support of bio-microarray in high-sensitive biorecognition.
Databáze: OpenAIRE