Hospitalization Increases the Risk of Acute Arthritic Flares in Gout: A Population-based Study over 2 Decades
| Autor: | Cynthia S. Crowson, Tim Bongartz, Zoran Kvrgic, Mohanad M. Elfishawi, Eric L. Matteson, Nour Zleik, Clement J. Michet |
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| Rok vydání: | 2018 |
| Předmět: |
musculoskeletal diseases
030203 arthritis & rheumatology medicine.medical_specialty business.industry Immunology Rate ratio medicine.disease Gout Population based study 03 medical and health sciences 0302 clinical medicine Rheumatology Internal medicine Statistical significance Cohort medicine Immunology and Allergy In patient 030212 general & internal medicine Hyperuricemia business Hospital stay |
| Zdroj: | The Journal of Rheumatology. 45:1188-1191 |
| ISSN: | 1499-2752 0315-162X |
| DOI: | 10.3899/jrheum.171320 |
| Popis: | Objective.To assess in-hospital gout flares in patients with gout.Methods.Hospitalizations were evaluated for gout flares in a cohort of Olmsted County, Minnesota, residents with incident gout in 1989–1992 or 2009–2010.Results.There were 429 patients followed up to 5 years. Of these, 169 patients experienced 454 hospitalizations. Hospitalization rates increased without reaching statistical significance from 1989–1992 to 2009–2010 [rate ratio (RR) 1.19, 95% CI 0.98–1.45]. The gout flare rate increased significantly during hospitalization (RR 10.2, 95% CI 6.8–14.5). In-hospital gout flare increased the average hospital stay by 1.8 days (p < 0.001).Conclusion.Hospitalization increased the risk of gout flares 10-fold. In-hospital gout flares were associated with longer hospitalization. |
| Databáze: | OpenAIRE |
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