Desmopressin (DDAVP) treatment in adult sleep-related enuresis
| Autor: | Roberto Mester, Alex Grinshpoon, Baruch Spivak, Abraham Weizman, Gregory Katz |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Vasopressin
business.industry medicine.drug_class Tricyclic antidepressant Bedtime Psychiatry and Mental health Neurology Enuresis Anesthesia medicine Pharmacology (medical) Nasal administration Neurology (clinical) Young adult medicine.symptom Prospective cohort study business Desmopressin medicine.drug |
| Zdroj: | Human Psychopharmacology: Clinical and Experimental. 12:505-507 |
| ISSN: | 1099-1077 0885-6222 |
| DOI: | 10.1002/(sici)1099-1077(199709/10)12:5<505::aid-hup916>3.0.co;2-a |
| Popis: | In an open prospective study we investigated the efficacy of intranasal administration of 1-desamino-8-D-arginine vasopressin (DDAVP) in enuretic adults during military service. Twelve male enuretic soldiers aged 18–19 years (18·9±0·5 years), with a history of resistance to tricyclic antidepressant treatment and to behavioural therapy, were included in the study. Patients were treated with 20–40 mg (bedtime dose) DDAVP. A significant decrease in the frequency of enuresis was demonstrated (3·4±4·3 versus baseline of 8·2±3·3 days, p=0·01). Four patients achieved complete dryness and four patients achieved partial response. It seems that intranasal DDAVP can be an effective and safe treatment in young adult sleep-related enuresis. © 1997 John Wiley & Sons, Ltd. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|