Changes in the biochemical indicators of metabolism in employees of the oil company
| Autor: | Marina A. Zemlyanova, Ekaterina V. Peskova, Juliya V. Koldibekova, Olga V. Pustovalova, Viktor M. Ukhabov |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Hygiene and sanitation. 101:1328-1333 |
| ISSN: | 2412-0650 0016-9900 |
| Popis: | Introduction. Due to the constant presence of harmful chemical components in the air of the working area at an oil-producing enterprise, the length of work experience exacerbates their negative impact on the human body, which can lead to dysmetabolic disorders. The purpose of the work is to assess changes in the biochemical parameters of metabolism in workers of an oil producing enterprise. Materials and methods. A study and assessment of the content of polycyclic aromatic hydrocarbons in the bioenvironments of workers, biochemical indicators of metabolic processes, statistical analysis, modelling of cause-and-effect relationships were carried out. Results. In oil and gas production operators, benzene and o-xylene are identified in the blood, the concentration of which is up to 1.5 times higher than that of workers not associated with the oil production process. There is and gain in the level of benzene in the blood up to 1.4 times, depending on the increase in work experience. Significant differences were found in the content of C-peptide, glucose, total cholesterol, HDL cholesterol, LDL cholesterol and triglycerides in oil and gas production operators relative to similar indicators in workers not exposed to chemical production factors of the enterprise. Among workers involved in oil and gas production, a dependence of an elevation of glucose and C-peptide in the blood serum on an increase in the concentration of benzene in the blood and the length of work experience was established; an increase in the level of total cholesterol, LDL cholesterol, triglycerides in the blood serum - only depending on the increase in work experience. Limitations. The conducted study takes into account the influence of only chemical factors and the duration of work experience on the health of oil production workers. Conclusions. The constant presence of polycyclic aromatic hydrocarbons in the air, in particular benzene and O-Cixille (up to 1.5 times higher than the MPC of the working area), leads to their increased concentration in the blood. In operators of oil and gas production there was established an increase in the level of a number of biochemical indicators of the negative effects of metabolic syndrome, which are dependent on the length of service and the content of benzene in the air of the working area. |
| Databáze: | OpenAIRE |
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