The regioselective annulation of N-methylpyridinium ylides with alkenes enabled by palladium catalysis: access to 3-unsubstituted indolizine derivatives

Autor: Quan Gou, Qianhua Zhu, Mengjiao Deng, Weiwei Li, Xing Ran, Jianfeng Xie, Huisheng Huang, Xiaoping Tan, Minghong Zhu
Rok vydání: 2022
Předmět:
Zdroj: Organic Chemistry Frontiers. 9:4719-4725
ISSN: 2052-4129
DOI: 10.1039/d2qo00555g
Popis: The first catalytic protocol for the regioselective [3 + 2] annulation of N-methyl pyridinium ylides with alkenes to establish various valuable 3-unsubstituted indolizine derivatives is accomplished via palladium catalysis at the unactivated position.
Databáze: OpenAIRE