Voltammetric determination of cocaine in confiscated samples

Autor:	Agustín Costa García, José Ramón Barreira Rodríguez, María Teresa Fernández Abedul, Paulino Tuñón Blanco
Rok vydání:	1991
Předmět:	Horizontal scan rate Chemistry Calibration curve Diffusion Electrode Charge transfer coefficient Electrochemistry Analytical chemistry Oxidation process Dosage form Analytical Chemistry
Zdroj:	Electroanalysis. 3:409-412
ISSN:	1521-4109 1040-0397
DOI:	10.1002/elan.1140030427
Popis:	The electrochemical behavior of the abuse drug cocaine has been studied. Cocaine undergoes an irreversible oxidation process on carbon paste electrodes. It was calculated that 2 electrons were involved, and the value obtained for the charge transfer coefficient was 0.362 ± 0.006. Comparative voltammetric experiments yielded an estimated diffusion coefficient value for cocaine of 0.27 × 10−5 cm2 s−1. A linear calibration plot from 1.0 × 10−6 to 1.0 × 10−4M was obtained by using a scan rate of 50 mV s−1. A simple and reproducible procedure is proposed for the determination of cocaine in illegal dosage forms confiscated by police authorities; the results agree with those of a HPLC-UV method.
Databáze:	OpenAIRE
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