Chiral organometallic NADH mimics: stereoselective reduction of ethyl benzoylformate utilising the homochiral auxiliary [(η5-C5H5)Fe(CO)(PPh3)] at C-3 and a chiral β-hydroxy-carboxamide derived from valinol at C-5

Autor:	Stephen G. Davies, Renato Skerlj, Vicky A. Burgess
Rok vydání:	1990
Předmět:	Chiral auxiliary medicine.drug_class Ethyl mandelate Stereochemistry Carboxamide chemistry.chemical_compound chemistry medicine Molecular Medicine Stereoselectivity Triphenylphosphine Valinol Aliphatic compound Enantiomeric excess
Zdroj:	J. Chem. Soc., Chem. Commun.. :1759-1762
ISSN:	0022-4936
DOI:	10.1039/c39900001759
Popis:	Homochiral complexes incorporating the chiral auxiliary [(η5-C5H5)Fe(CO)(PPh3)] at C-3 and a chiral β-hydroxy-carboxamide, derived from valinol, at C-5 reduce ethyl benzoylformate to ethyl mandelate in greater than 97% enantiomeric excess.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ac517985b714a0aa6c8e4a1e302f9bdf https://doi.org/10.1039/c39900001759 Zobrazit plný text záznamu