ChemInform Abstract: Michael Reactions of Titanium Enolates of Glycolic Acid Derivatives with the Weinreb and Morpholine Amides of Acrylic Acid

Autor:	Carles Rodríguez-Escrich, Fèlix Urpí, Anna Olivella, Jaume Vilarrasa
Rok vydání:	2008
Předmět:	chemistry.chemical_compound Enantiopure drug Chemistry Morpholine Synthon Organic chemistry chemistry.chemical_element General Medicine Glycolic acid Adduct Titanium Conjugate Acrylic acid
Zdroj:	ChemInform. 39
ISSN:	1522-2667 0931-7597
Popis:	The conjugate additions of titanium enolates of glycolate-derived chiral oxazolidin-2-ones to various Michael acceptors have been evaluated as an entry to enantiopure 1,2,5-trioxygenated and related synthons. α,β-unsaturated Weinreb and morpholine amides do react under suitable conditions and their adducts can be converted to diverse C1−C5 chiral fragments.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ac4ecf9602288362ed491fec2472f636 https://doi.org/10.1002/chin.200825048 Zobrazit plný text záznamu Plný text