Measurement of the anti-inflammatory and irritant properties of various agents in the rat
| Autor: | E. Khedouri, P.J. Warne, G.B. West |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Pharmacology
chemistry.chemical_classification Aspirin medicine.diagnostic_test Chemistry medicine.drug_class Hematocrit Hemoconcentration Anti-inflammatory Amino acid Carrageenan Peritoneal cavity Acetic acid chemistry.chemical_compound medicine.anatomical_structure Anesthesia medicine medicine.drug |
| Zdroj: | Journal of Pharmacological Methods. 2:157-160 |
| ISSN: | 0160-5402 |
| Popis: | Indomethacin exerted its anti-inflammatory action in the carrageenan paw edema model without producing an alteration in the hematocrit and without exerting an irritant effect in the peritoneal cavity. Aspirin was anti-inflammatory and irritant but it did not result in hemoconcentration. Amino acid esters and esters of acetic acid inhibited the carrageenan paw edema but they were irritant and altered the hematocrit, and so were not typical anti-inflammatory drugs. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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