| Autor: |
Amal Hajri, Abderrahmane Lamnaouar, Kabira Falousse, Driss Erreguibi, Rachid Boufettal, El Jay Saad Rifki, Chehab Farid |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Archives of Clinical Gastroenterology. 9:004-007 |
| ISSN: |
2455-2283 |
| Popis: |
Introduction: Adenosquamous Carcinoma (ASC) of the anus presenting both glandular and squamous histopathologic features is a rare colorectal neoplasm. Case presentation: A 63-year-old man presented with a one-year history of intermittent rectal pain and bleeding on a perineal fistula. Pathological analysis of the surgical specimen revealed adenosquamous carcinoma of the anus, The patient received neoadjuvant treatment with chemotherapy and radiotherapy over a period of five weeks. then he underwent abdominoperineal resection and a permanent colostomy. Histology revealed invasive adenosquamous carcinoma on the resection specimen and the patient was started on adjuvant therapy with FOLFIRINOX. Discussion: Primary ASC of the colon and rectum are extremely rare clinical entities with poor prognosis. Most of the data come from individual case reports and a few small series, making it a challenge to understand the histogenesis of the disease. And the treatment modalities are not yet well codified, which has an impact on overall survival. Conclusion: Early diagnosis and radical surgery with other available therapeutic modalities can improve clinical outcomes. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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