The role of hemorheological factors in hypertensne retinopathy
| Autor: | Krisztián Tóth, B. Kovacs, I. Juricskay, Judit Vekasi |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
medicine.medical_specialty
Pathology Physiology business.industry Eye disease Hematology Fundus (eye) medicine.disease Pathogenesis Fibrinogen levels Hypertensive retinopathy Physiology (medical) Internal medicine medicine Cardiology Cardiology and Cardiovascular Medicine Complication business Pathological Retinopathy |
| Zdroj: | Clinical Hemorheology and Microcirculation. 16:187-192 |
| ISSN: | 1386-0291 |
| Popis: | Hemorheological factors play an important role in the pathogenesis of different cardiovascular diseases. In the present study the fundus appearance and hemorheological parameters (plasma and whole blood viscosity *WBV* by capillary viscosimetry; fibrinogen level by the Clauss method) of 33 hypertensive patients (23 females, 10 males; mean age: 55 years) were examined. The fundus appearance showed retinopathy in all the cases between stages I-III. All the measured hemorheological parameters of the examined patients were in the pathological range (WBV at 90 lis: 5.18 mPas) and were significantly (p < 0.01) higher than in healthy controls (WBV at 90 lis: 4.18 mPas). The hemorheological factors showed a parallel deterioration with the fundus appearance, namely their values were significantly (p < 0.01) higher in patients with a fundus appearance stage III (WBVat 90 lis: 6.02 mPas) than stage I (WBVat 90 lis: 4.51 mPas). Our results show that there is a correlation between hemorheological parameters and fundus appearance in hypertensives, and this suggests that hemorheological factors may playa role in the development of hypertensive retinopathy. |
| Databáze: | OpenAIRE |
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