Synthetic, Spectroscopic, and Biological Aspects of Triorganosilicon(IV) Complexes of Tridentate Schiff Bases
| Autor: | Jai Devi, Rajesh Malhotra, Suman Kumari, Sonika Asijaa |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
biology
Chemistry Ligand Organic Chemistry Aspergillus niger Biological activity Bacillus subtilis biology.organism_classification Antimicrobial medicine.disease_cause Biochemistry Medicinal chemistry Inorganic Chemistry chemistry.chemical_compound Deprotonation medicine Organic chemistry Escherichia coli Organosilicon |
| Zdroj: | Phosphorus, Sulfur, and Silicon and the Related Elements. 187:1409-1417 |
| ISSN: | 1563-5325 1042-6507 |
| DOI: | 10.1080/10426507.2012.686546 |
| Popis: | Hexacoordinated organosilicon complexes of type R3Si(L) (R = ethyl, butyl, phenyl; HL = ligand, obtained by the condensation of 4-aminoantipyrine with 2-hydroxyacetophenone, 2-hydroxybenzophenone, 2-hydroxybenzaldehyde, and 2-hydroxynapthaldehyde) have been synthesized and characterized by elemental analysis, molar conductance, and spectroscopic studies (IR, 1H, 13C, and 29Si NMR). The spectroscopic studies indicated that the ligands acted as tridentate coordinating through azomethine nitrogen, carbonyl oxygen, and oxygen of hydroxyl after deprotonation to the central silicon atom. The ligands and their organosilicon complexes have been evaluated for antimicrobial activities against fungi (Aspergillus niger and Candida albicans), and against Gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis), and Gram-negative bacteria (Escherichia coli). The aim of the present work is to synthesize novel eco-friendly fungicides and bactericides and to study the effect of the biological activity of... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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