Clinical characteristics of malignant melanomas developing in persons with dysplastic nevi

Autor:	A F Vinokur, R. J. Friedman, D S Rigel, E. R. Heilman, Jason K. Rivers, Alfred W. Kopf, Marcia J. Levenstein
Rok vydání:	1990
Předmět:	Cancer Research medicine.medical_specialty business.industry Follow up studies Newly diagnosed medicine.disease Dermatology Breslow Thickness Oncology Clinical investigation Dysplastic nevus Medicine Pigmented lesion business
Zdroj:	Cancer. 65:1232-1236
ISSN:	1097-0142 0008-543X
DOI:	10.1002/1097-0142(19900301)65:5<1232::aid-cncr2820650533>3.0.co;2-8
Popis:	A total of 452 patients with dysplastic nevi (DN) were followed prospectively by repetitive, complete cutaneous examinations in order to determine the clinical features of early malignant melanomas (MM) arising in them. Sixteen patients (3.5%) developed 18 newly diagnosed MM during an average follow-up period of 27 months. Twelve of the 18 MM were in situ and all of the primary invasive MM diagnosed prospectively in this follow-up were less than 0.89 mm in Breslow thickness, implying an excellent prognosis. The principal clinical clue to the diagnosis of MM was change in a preexisting pigmented lesion. Total-body photographs were very useful in helping to identify the early MM in these patients.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::abed44b404302646e558dcfcad7e352e https://doi.org/10.1002/1097-0142(19900301)65:5<1232::aid-cncr2820650533>3.0.co Zobrazit plný text záznamu Plný text