Abstract 1358: Structure-based drug design of 3-site binding, high affinity inhibitors of S100B in malignant melanoma
Autor: | Michael C. Cavalier, David J. Weber, David J. Maloney, Mohd. Imran Ansari, Andrew Coop, Diane K. Luci, Alexander D. MacKerell, Ajit Jadhav, Paul T. Wilder, Lei Fang |
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Rok vydání: | 2016 |
Předmět: | |
Zdroj: | Cancer Research. 76:1358-1358 |
ISSN: | 1538-7445 0008-5472 |
Popis: | An especially predictive biomarker when used in combination with other diagnostic indicators, S100B is elevated in >90% of malignant melanoma (MM) patients and its protein level correlates directly with poor survival ( Citation Format: Michael C. Cavalier, Paul T. Wilder, Diane Luci, David J. Maloney, Lei Fang, Mohd. Imran Ansari, Alexander D. MacKerell, Andrew Coop, Ajit Jadhav, David J. Weber. Structure-based drug design of 3-site binding, high affinity inhibitors of S100B in malignant melanoma. [abstract]. In: Proceedings of the 107th Annual Meeting of the American Association for Cancer Research; 2016 Apr 16-20; New Orleans, LA. Philadelphia (PA): AACR; Cancer Res 2016;76(14 Suppl):Abstract nr 1358. |
Databáze: | OpenAIRE |
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