Effects of Elasticity on Wall Shear Stress in Patient-Specific Aneurysm of Cerebral Artery
| Autor: | Kazuhiro Watanabe, Nadia Shaira Shafii, Hitomi Anzai, Gaku Tanaka, Kahar Osman, Atsushi Saito, Ryuhei Yamaguchi, Makoto Ohta, Taihei Kotani, Simon Tupin, Ahmad Zahran Md Khudzari |
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| Rok vydání: | 2019 |
| Předmět: |
Materials science
Deformation (mechanics) Cerebral arteries Mechanics medicine.disease Stagnation point Aneurysm Particle image velocimetry medicine.artery Middle cerebral artery cardiovascular system medicine Shear stress cardiovascular diseases Elasticity (economics) circulatory and respiratory physiology |
| Zdroj: | Journal of Flow Control, Measurement & Visualization. :73-86 |
| ISSN: | 2329-3330 2329-3322 |
| Popis: | The behavior of wall shear stress (WSS) was previously reported in a deformable aneurysm model using fluid-structure interactions. However, these findings have not been validated. In the present study, we examined the effect of elasticity (i.e., deformation) on wall shear stress inside a cerebral aneurysm at the apex of a bifurcation using particle image velocimetry in vitro. The flow model simulated a human patient-specific aneurysm at the apex of the bifurcation of the middle cerebral artery. Flow characteristics by wall elasticity were examined for both elastic and non-deformable aneurysm models with pulsatile blood flow. The absolute temporally- and spatially-averaged WSS along the bleb wall was smaller in the elastic model than that in the non-deformable model. This small WSS may be related to attenuation of the WSS. Further, the WSS gradient had a finite value near the stagnation point of the aneurysm dome. Finally, the WSS gradient near the stagnation point was slightly smaller in the elastic model than that in the non-deformable model. These data suggest that elasticity of the aneurysm wall can affect the progression and rupture of aneurysms via hemodynamic stress. |
| Databáze: | OpenAIRE |
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