Synthesis of New Antibiotic Agent Based on Mannich Reaction

Autor: Saripah S. S. A. Azziz, Saif M. Hassan, Zahraa H. Khudhair, Mahmood J. Jawad, Alhussein A. Majhool, Ameer H. Idan, Ahmed K. O. Aldulaimi
Rok vydání: 2022
Předmět:
Zdroj: INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY. 12:1428-1432
ISSN: 0975-4415
Popis: Three new anti-bacterial compounds were designed and synthesized via the Mannich reaction and evaluated in vitro against different species of bacteria. The compounds have been characterized based on Fourier transform infrared (FTIR), 1HNMR, and Carbon-13 Nuclear magnetic resonance, A significant part of the compounds obtained, showed anti-bacterial activity towards Gram-positive and Gram-negative species.
Databáze: OpenAIRE