[123I]-IMP single-photon emission computed tomography imaging in visual snow syndrome: A case series

Autor: Jin Nakahara, Yu Iwabuchi, Mamoru Shibata, Tadaki Nakahara, Masahiro Jinzaki, Kei Tsutsumi, Hirokazu Fujiwara, David W. Dodick, Masashi Kameyama, Tsubasa Takizawa
Rok vydání: 2020
Předmět:
Zdroj: Cephalalgia. 40:1671-1675
ISSN: 1468-2982
0333-1024
DOI: 10.1177/0333102420950454
Popis: Background Visual snow syndrome (VSS) is a neurological condition characterized by persistent flickering dots in the visual fields, palinopsia, enhanced entoptic phenomenon, photophobia, and nyctalopia. Neuroimaging evidence supports the role of the visual association cortex in visual snow syndrome. Case series: We provided clinical care to three patients with visual snow syndrome, in whom [123I]-IMP single-photon emission computed tomography (SPECT) imaging was performed. Case 1 was a 21-year-old male with a past history of migraine with aura who exhibited visual snow and entoptic phenomenon. In this patient, [123I]-IMP SPECT imaging revealed right occipital and temporal hypoperfusion with a distribution matching the ventral visual stream. [123I]-IMP SPECT imaging detected only mild bilateral frontal hypoperfusion in Case 2 and no overt abnormalities in Case 3. Conclusion Although visual snow syndrome seems to be a heterogenous condition, our observations indicate that abnormal visual processing within the ventral visual stream may play a role in the pathogenesis of this condition.
Databáze: OpenAIRE
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