A pH sensitive fluorescent cyanine dye for biological applications

Autor: D. Dougal Burns, Mark S. Briggs, Susan J. Gregory, Michael E. Cooper
Rok vydání: 2000
Předmět:
Zdroj: Chemical Communications. :2323-2324
ISSN: 1364-548X
1359-7345
DOI: 10.1039/b007108k
Popis: A pentamethine cyanine dye has been synthesised that is fluorescent when protonated, becoming non-fluorescent upon proton abstraction. The probe has a pKa of 7.5, with observable changes in the fluorescent emission properties across a pH range of 6.0–8.0, therefore providing a useful probe for studying pH in biological media.
Databáze: OpenAIRE