A pH sensitive fluorescent cyanine dye for biological applications
Autor: | D. Dougal Burns, Mark S. Briggs, Susan J. Gregory, Michael E. Cooper |
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Rok vydání: | 2000 |
Předmět: | |
Zdroj: | Chemical Communications. :2323-2324 |
ISSN: | 1364-548X 1359-7345 |
DOI: | 10.1039/b007108k |
Popis: | A pentamethine cyanine dye has been synthesised that is fluorescent when protonated, becoming non-fluorescent upon proton abstraction. The probe has a pKa of 7.5, with observable changes in the fluorescent emission properties across a pH range of 6.0–8.0, therefore providing a useful probe for studying pH in biological media. |
Databáze: | OpenAIRE |
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