Healing of ischemic skin ulcers in patients with connective tissue diseases with oral anticoagulant treatment

Autor: Alexander Rozin, Abraham M. Nahir, Doron Markovits, Yolanda Braun-Moscovici, Daniel Schapira, Alexandra Balbir-Gurman
Rok vydání: 2008
Předmět:
Zdroj: International Journal of Rheumatic Diseases. 11:127-130
ISSN: 1756-185X
1756-1841
Popis: Objective: Ischemic skin ulcers (ISU) are a well-known complication of systemic sclerosis (SSc) and are often refractory to conventional therapy. The influence of treatment with oral anticoagulants (OAC) on ISU healing in SSc patients was analysed. Methods: The medical records of SSc patients with ISU who were treated with OAC for at least 4 months between the years 2002–06 were reviewed. Results: Fifteen patients with SSc and ISU were treated with OAC. The mean achieved International Normalized Ratio was 2.2 (± 0.35). Treatment with OAC significantly reduced the pain visual analogue scale (P
Databáze: OpenAIRE