Obesity and decreased vibration perception associated with premature cardiovascular mortality in a single center prospective study of people with diabetes

Autor:	M D Tomic, Milovan Petrovic, M T Tomic, D Andric, Tanja Popov, M Stefanovic, S Andric, D Tesic, Tatjana Miljković
Rok vydání:	2021
Předmět:	Vibration perception Pediatrics medicine.medical_specialty business.industry Diabetes mellitus medicine Cardiology and Cardiovascular Medicine Prospective cohort study Single Center medicine.disease business Obesity Cardiovascular mortality
Zdroj:	European Heart Journal. 42
ISSN:	1522-9645 0195-668X
DOI:	10.1093/eurheartj/ehab724.2491
Popis:	Background and aims The aim of this prospective, single center study was to define factors associated with early cardiovascular mortality in diabetes. Materials and methods 1345 patients under age 75 were included who were undergoing assessment of their diabetes between January 2008 and May 2010 as part of standard practice in a specialist clinic at a regional teaching hospital in Serbia. Peripheral artery disease (PAD) was assessed by audible Doppler waveform and ABPI with cut-offs >1.4 and Results Those who died (n2=70) were more frequently male (60 vs. 45.3%, p=0.08), younger (66.4±7.4 vs. 79.9±3.4, p6, there were significant differences in TEA/CVI (4.2 [95% CI: 1.6–10.9)], p=0.003), PAD (3.9 [95% CI: 1.8–8.8)], p Conclusion Decreased VPT, the presence of PAD on clinical testing and higher maximum estimated lifetime BMI are strongly associated with premature cardiovascular death. These measures may be independent markers of greater risk of reduced life expectancy. Funding Acknowledgement Type of funding sources: None.
Databáze:	OpenAIRE
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