New rearranged products from the methylation of 13-oxobaccatin III

Autor:	Walter Ceccarelli, Maria Menichincheri, Vittorio Pinciroli, Domeico Fusar-Bassini, Nicola Mongelli, Ermes Vanotti
Rok vydání:	1996
Předmět:	Stereochemistry Organic Chemistry Ring (chemistry) Biochemistry Medicinal chemistry Sodium hydride chemistry.chemical_compound chemistry Decalin Intramolecular force Drug Discovery Molecule Aldol condensation Two-dimensional nuclear magnetic resonance spectroscopy Methyl iodide
Zdroj:	Tetrahedron Letters. 37:9365-9368
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(97)82965-6
Popis:	Treatment of 7-triethylsilyl-13-oxobaccatin III (1) with sodium hydride and methyl iodide gave the methylated ten-membered ring compound 2 that rearranged, via intramolecular aldol condensation, to unsaturated decalin ring system (3, 4, 5). These molecules were characterized by 1D and 2D NMR tecniques.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ab7b9c820f32de06a2174ee7ec809153 https://doi.org/10.1016/s0040-4039(97)82965-6 Zobrazit plný text záznamu Full Text from ScienceDirect