Pleurodosis through drain for malignant pleural effusion : a case control study
| Autor: | H. Ghrairi, Salsabil Bouafia, M. Loukil, Narjess Abid, Nada Gader, Slim Kalboussi, Ines Laouini |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
education.field_of_study
medicine.medical_specialty Lung medicine.diagnostic_test business.industry Population medicine.disease Chest pain Surgery medicine.anatomical_structure Breast cancer medicine Thoracoscopy Adenocarcinoma Malignant pleural effusion medicine.symptom Lung cancer business education |
| Zdroj: | Interventional pulmonology. |
| Popis: | Introduction: malignant pleural effusion (MPE) is typically recurrent and associated with significant morbidity. Thus, pleurodosis is often necessary to avoid the reaccumulation of pleural fluid providing a better quality of life. Methods: we retrospectively studied the medical reports of 60 patients who underwent medical pleurodosis for MPE during the period between January 2014 and july 2018. Results: the mean age was 61 ± 14 years [27-89 years]. The population sex ratio was 1, 61. The mean delay of consultation was 44, 5 days [3-135 days]. The principal etiology of the MPE was the primary lung cancer (PLC) (73%) followed by the breast cancer (13.3%). In case of PLC, adenocarcinoma was the most frequent histological type. All patients had chest drainage. The mean quantity of evacuated pleural fluid was 4020 ± 3200 ml. MP was done after lung re-expansion on average after 3.22 ± 2.1 days [1 -11 days] of pleural drainage. The sclerosant used were talc slurry for 56 patients (93.33%) and Povidone-iodine for 4 patients (6.66%). Intolerance such as chest pain, fever and dyspnea was observed in 20% of cases. The MP success rate was 75% (45 patients) and was similar for talc slurry and Povidone-iodine (75.8% vs 75.1% ; p=0.8). Mean survival after pleurodosis was 139 ±114 days. There was no correlation between sclerosant used and survival (talc: 433 ± 123 days, Povidone-iodine 252 ± 54 days; p=0.163). Conclusion: Our study demonstrates that MP is effective and well tolerated in the majority of cases. This procedure may represent an interesting alternative to surgical thoracoscopy. |
| Databáze: | OpenAIRE |
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