Emulsifier-Free Emulsion Copolymerization of Methyl Methacrylate As a Method of Obtaining Cationic Particles for Diagnostics of Tick-Borne Encephalitis Virus
Autor: | B. M. Shabsel’s, G. A. Pankova, N. N. Shevchenko, Vadim A. Baigildin, Svetlana Laishevkina |
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Rok vydání: | 2020 |
Předmět: |
010304 chemical physics
biology Ethylene glycol dimethacrylate Dispersity Cationic polymerization Sorption 02 engineering and technology Surfaces and Interfaces 021001 nanoscience & nanotechnology biology.organism_classification Methacrylate 01 natural sciences Tick-borne encephalitis virus chemistry.chemical_compound Colloid and Surface Chemistry chemistry 0103 physical sciences Copolymer Physical and Theoretical Chemistry Methyl methacrylate 0210 nano-technology Nuclear chemistry |
Zdroj: | Colloid Journal. 82:208-216 |
ISSN: | 1608-3067 1061-933X |
Popis: | Cross-linked cationic particles 150–300 nm in diameter have been synthesized via single-stage emulsifier-free copolymerization of methyl methacrylate and 2-aminoethyl methacrylate hydrochloride in the presence of cross-linking agents (ethylene glycol dimethacrylate and N,N'-methylenebisacrylamide). Factors that enable one to control the morphology and polydispersity of the resulting particles have been determined. It has been shown that the dispersions of the particles are aggregatively stable in physiological solutions and after the sorption of biologically active molecules. The synthesized particles can be used for efficient revealing tick-borne encephalitis virus via latex agglutination reaction, with the analysis time being no longer than 10 min. |
Databáze: | OpenAIRE |
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