A cardiac pacemaker model incorporating frequency control by the autonomic nervous system

Autor:	H. M. Power, A. K. Kamaltjddin
Rok vydání:	1974
Předmět:	Autonomic nervous system Control and Systems Engineering Chemistry medicine.medical_treatment Automatic frequency control Circulatory system medicine Stimulation Neuroscience Cardiac pacemaker Computer Science Applications Theoretical Computer Science
Zdroj:	International Journal of Systems Science. 5:673-685
ISSN:	1464-5319 0020-7721
Popis:	An electronic model of a cardiac pacemaker cell is developed from a study of the Hodgkin—.Huxley equations describing the dynamic behaviour of excitable tissue membranes. The model is based on the functional hypothesis that the controlling factor is the leakage conductance of the membrane to sodium ions and that this is increased by stimulation of the sympathetic nerves and decreased by stimulation of the parasympathetic nerves. The resulting model shows close agreement with experimental results obtained by Levy and Ziesko on the heart of the anaesthetised dog. The model forms part of an circulatory-parameter analogue of the human circulatory system currently being constructed as an aid to studying the manner in which the parameters and control loops of this system adapt to prolonged periods of heavy exercise.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ab5a5c844ff0f844d598c9a5dbd932fb https://doi.org/10.1080/00207727408920132 Zobrazit plný text záznamu