Laboratory markers of premature aging and metabolic syndrome in liquidators of consequences of Chernobyl accident
| Autor: | V. Yu. Rybnikov, N. A. Alkhutova, N. А. Kovyazina |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Premature aging
medicine.medical_specialty 030219 obstetrics & reproductive medicine Triiodothyronine business.industry 030209 endocrinology & metabolism Context (language use) medicine.disease Pathogenesis 03 medical and health sciences 0302 clinical medicine Endocrinology Internal medicine Androgen deficiency medicine Metabolic syndrome Adaptation business Testosterone |
| Zdroj: | Medical alphabet. :59-63 |
| ISSN: | 2078-5631 |
| DOI: | 10.33667/2078-5631-2021-13-59-63 |
| Popis: | In this paper, the metabolic syndrome (MS) is considered as a manifestation of an excessive adaptive response of the body, which underlies premature aging. It is relevant to search for new early markers of MS formation in LPA in the context of modern ideas about the role of universal mechanisms of adaptation and stress-induced premature aging in its pathogenesis. The data obtained by the authors allow us to consider the relative androgen deficiency as a predictor of the formation of MS in LPA. The results of the study demonstrate that the levels of triiodothyronine and DHEAS serve as early markers of the formation of MS, while the testosterone/estradiol ratio is a universal laboratory indicator of accelerated aging of the body and MS. |
| Databáze: | OpenAIRE |
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