Seborrheic dermatitis prevalence in HIV patients
| Autor: | Magdalena Constantin, Irina Magdalena Dumitru, Facultatea de Medicină generală a Universităţii „Ovidius', Constanţa, România, Aurelia Hangan, Anca Raducan, Spitalul Clinic de Boli infecţioase, Constanţa, România, Universitatea de Medicină şi Farmacie „Carol Davila', Bucureşti, România, Sorin Rugină, Clinica Ii Dermatologie, Spitalul Clinic Colentina, Bucureşti, România |
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| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Romanian Journal of Infectious Diseases. 18:131-137 |
| ISSN: | 2069-6051 1454-3389 |
| Popis: | Objective. Highlighting seborrheic dermatitis prevalence in HIV patients and evaluating clinico-therapeutical correlations. Material and methods. Between 1.10.2011 – 31.12.2014 we performed a prospective study on a group of 121 HIV-positive patients hospitalized in the HIV Adults Department in the Infectious Diseases Hospital, Constanta, to determine the prevalence, clinical particularities and treatment response of seborrheic dermatitis in HIV + patients. Results. Seborrheic dermatitis has been reported in 33.05% of patients, predominantly male (M:F = 9:1), with peak incidence in the 20-30 age group. Lesions prevalence according to the site of seborrheic dermatitis was: face (15%), scalp (22.5%), face and scalp (45%), chest (12.5%). In terms of clinical severity, 27.5% patients had mild seborrheic dermatitis, while 62.5% had moderate seborrheic dermatitis, and 10% were diagnosed with the severe form. Therapeutic response was evaluated at day 7, 14 and after 8 weeks, assessing the decrease/disappearance of erythema and flaking, and pruritus improvement/remission. After 8 weeks of treatment, complete remission was reported in 70% patients. However, HIV+ patients with seborrheic dermatitis had between 2-5 episodes per year, relapses being reported at 4 to 12 weeks after discontinuation of treatment, mean 7 weeks. Conclusions. The present study indicates a moderate prevalence of seborrheic dermatitis in hospitalized HIV+ patients. Although clinical manifestations do not differ from those of seborrheic dermatitis in seronegative patients, the clinical course of disease reveals the extensive character of seborrheic dermatitis in HIV+ patients with more severe lesions, refractory to treatment, and frequent recurrences, even in patients receiving prolonged treatment. |
| Databáze: | OpenAIRE |
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